Maximizing the Benefits of Philanthropic Hearing Programs

Maximizing the benefits and minimizing the risks of intervention programs to address micronutrient malnutrition: symposium report

Interventions to address micronutrient deficiencies have large potential to reduce the related disease and economic burden. However, the potential risks of excessive micronutrient intakes are often not well determined. During the Global Summit on Food Fortification, 9-11 September 2015, in Arusha, a symposium was organized on micronutrient risk-benefit assessments. Using case studies on folic a...

Maximizing benefits from crowdsourced data

Crowds of people can solve some problems faster than individuals or small groups. A crowd can also rapidly generate data about circumstances affecting the crowd itself. This crowdsourced data can be leveraged to benefit the crowd by providing information or solutions faster than traditional means. However, the crowdsourced data can hardly be used directly to yield usable information. Intelligen...

REAP REWARDS: Maximizing Benefits from Reviewer Comments

Maximizing the benefits of off-target kinase inhibitor activity.

Investigators report the identification of novel mutant-specific inhibition of EGF receptor (EGFR) T790M by bis-indole-based inhibitors of protein kinase C using a small-molecule cancer cell line-based screening platform. This study shows the power of high-throughput drug screening in cancer cell lines and provides new lead scaffolds for optimization against resistant EGFR mutants in lung cancer.

Maximizing the benefits of antiretroviral therapy for key affected populations

INTRODUCTION Scientific research has demonstrated the clinical benefits of earlier initiation of antiretroviral treatment (ART), and that ART can markedly reduce HIV transmission to sexual partners. Ensuring universal access to ART for those who need it has long been a core principle of the HIV response, and extending the benefits of ART to key populations is critical to increasing the impact o...